Biochemistry (BIOC)

BIOC 110: General Biochemistry (4 Credits)

A study of central biochemical principles and the chemical changes that take place in living systems that are governed by these principles. Topics include: amino acid chemistry, protein folding and activity, catalysis and kinetics, selected metabolic pathways and their regulation, the biochemistry of carbohydrates, lipids, and the nucleic acids. Lecture (4 per week).

Prerequisite(s): CHEM 108

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BIOC 141: Protein Chemistry and Enzymology (3 Credits)

A study of protein structure with emphasis on the chemical constraints on structure, the chemical forces that stabilize various structures, and how different protein structures support specific biochemical functions. These functions include facilitating changes in covalent structure or binding of other molecules by proteins. Models for regulation of catalytic activity and/or molecular association are examined. Protein functions are also examined in the context of metabolic and regulatory pathways.

Prerequisite(s): CHEM 106 and CHEM 018

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BIOC 142: Metabolism and Proteomics (3 Credits)

A study of metabolic pathways, the relationships among them, the regulation of flux through these pathways, and constraints on pathways at the level of organ and organism. Both biosynthetic and biodegradative pathways will be examined; limited treatment of polymerization reactions. Pathways will be placed in the context of cells' proteomes.

Prerequisite(s): BIOC 141

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BIOC 143: Analytical Biochemistry (3 Credits)

A study of the laboratory tools and techniques of biochemistry; an examination of the chemical and physical principles that underlie these techniques. The techniques include those related to chemical and biochemical reactivity, separation of biological molecules, and the spectroscopic study of these molecules.

Prerequisite(s): BIOC 141

Note(s): BIOC 141 may be either a prerequisite or a corequisite depending on semester offered.

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BIOC 179: Directed Research (1-3 Credits)